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Recombinant Canine Distemper Virus Fusion glycoprotein F0 (F), C-His

Cat. No.VG9C416

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Canine Distemper Virus Fusion glycoprotein F0 (F), C-His is a recombinant protein expressed from Mammalian Cells. Its predicted molecular weight is 54.5 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System Mammalian Cells
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 54.5 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 0mM Tris, 500mM Nacl, 2M Urea, 10%glycerol, pH 7.4.

Target Information

Canine distemper virus fusion glycoprotein F0 (F) is a key protein in the canine distemper virus (CDV) that facilitates viral entry into host cells by mediating membrane fusion. Initially synthesized as an inactive precursor, F0, it trimerizes and is cleaved into two subunits, F1 and F2, which are crucial for its function. The F protein is activated by furin cleavage, transitioning from a prefusion to a postfusion conformation, which is associated with membrane merging and viral entry. This protein is also a major target for immune responses, making it significant for vaccine development and understanding viral pathogenesis.

Protein Canine Distemper Virus Fusion glycoprotein F0 (F)
Gene ID 1489793
UniProt ID P12569

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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