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Recombinant Canine Interleukin 1 Receptor Type 2 (IL1R2), C-Fc

Cat. No.AP2C34

Product TypeAnimal Proteins

Size 100 μg

Product Overview

BioVenic's Recombinant Canine Interleukin 1 Receptor Type 2 (IL1R2), C-Fc is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 64.8 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cell
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 64.8 kDa
Physical State Lyophilized
Formulation pH 7.4. 5 % trehalose and mannitol are added as protectants.

Target Information

Canine Interleukin 1 Receptor Type 2 (IL1R2) is a decoy receptor that binds to IL-1α and IL-1β, preventing their interaction with the signaling receptor IL1R1 and thereby inhibiting inflammatory signaling. In dogs, IL1R2 plays a critical role in regulating immune responses and reducing inflammation, making it a potential therapeutic target for inflammatory and autoimmune diseases. It is expressed in various tissues and immune cells, including neutrophils, and helps modulate the balance between pro-inflammatory and anti-inflammatory pathways.

Protein Canine Interleukin 1 Receptor Type 2 (IL1R2)
Protein Synonym IL1R2C; IL1R-2
Gene ID 481330
UniProt ID A0A8I3NJ31

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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