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Recombinant Canine Interleukin 6 (IL6)
Product Overview
BioVenic's Recombinant Canine Interleukin 6 (IL6) is a recombinant protein expressed from Baculovirus-Insect Cell. Its predicted molecular weight is 22.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Canine interleukin-6 (IL-6) is a multifunctional cytokine that plays a significant role in immune responses, inflammation, and the acute phase reaction. It is produced by various cells including T cells, B cells, monocytes/macrophages, fibroblasts, hepatocytes, keratinocytes, astrocytes, endothelial cells, and various tumor cells. IL-6 is involved in the regulation of immune responses, particularly in the activation of B cells, T cells, and the acute phase proteins in the liver. It also plays a role in the pathogenesis of various inflammatory and autoimmune diseases, as well as in the promotion of cancer cell growth and survival. IL-6 is a crucial mediator in the communication between immune cells and is essential for maintaining immune homeostasis in dogs.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.