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Recombinant Bovine Natriuretic Peptides A (NPPA)
Product Overview
BioVenic's Recombinant Bovine
Natriuretic Peptides A (NPPA) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 19.8 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine natriuretic peptides A, also known as A-type natriuretic peptides, are a group of hormones that include atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). These peptides are synthesized primarily in the heart and have similar structures. They exert their biological actions, which include natriuresis (increased excretion of sodium in the urine) and vasodilation (widening of blood vessels), by binding to specific receptors on target organs. In Bovine, these peptides play a role in maintaining cardiovascular homeostasis, regulating blood pressure, and managing fluid balance within the body. They also have been shown to have effects on the renal system, potentially influencing the development and homeostasis of blood vessels and lymphatic vessels, similar to their roles in other mammals.
Natriuretic Peptides A (NPPA)
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.