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Recombinant Bovine Natriuretic Peptides A (NPPA), N-His

Cat. No.AP9C443

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine
Natriuretic Peptides A (NPPA), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 20.8 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 20.8 kDa
Molecular Weight 12 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Bovine natriuretic peptides A, also known as A-type natriuretic peptides, are a group of hormones that play a significant role in maintaining cardiovascular homeostasis. They are produced by cardiomyocytes and include atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). These peptides have similar gene structures and exert protective effects on cardiovascular physiology, such as anti-hypertrophy, anti-fibrosis, myocardial relaxation, and blood pressure regulation. In Bovine, CNP has been shown to play a key role in sustaining oocyte meiotic arrest and enhancing the developmental competence of oocytes through the activation of CREB, which is important for mitochondrial biogenesis and oocyte cytoplasmic maturation.

Protein Bovine
Natriuretic Peptides A (NPPA)
Protein Synonym PND; Prepronatriodilatin; Cardiodilatin-related peptide
Gene ID 281355
UniProt ID P07501

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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