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Recombinant Canine Serine/threonine-Protein Kinase Receptor (ACVR1), C-Fc

Cat. No.AP2C32

Product TypeAnimal Proteins

Size 100 μg

Product Overview

BioVenic's Recombinant Canine Serine/threonine-Protein Kinase Receptor (ACVR1), C-Fc is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 38.6 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cell
Purity >95% (SDS-PAGE)
Predicted Molecular Weight 38.6 kDa
Physical State Lyophilized
Formulation pH 7.4. 5 % trehalose and mannitol are added as protectants.

Target Information

Canine Serine/threonine-Protein Kinase Receptor (ACVR1) is a key receptor involved in the TGF-β signaling pathway, regulating various biological processes in dogs. It is a type I receptor for bone morphogenetic proteins (BMPs) and is crucial for skeletal development, bone formation, and tissue repair. In veterinary medicine, ACVR1 is studied for its role in bone and cartilage disorders, as well as its potential as a therapeutic target for conditions involving abnormal bone growth. Mutations in ACVR1 have been associated with fibrodysplasia ossificans progressiva (FOP), a rare condition characterized by the formation of ectopic bone.

Protein Canine Serine/threonine-Protein Kinase Receptor (ACVR1)
Protein Synonym ACVR1
Gene ID 477603
UniProt ID A0A8I3PSN0

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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