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Recombinant Canine Metalloproteinase Inhibitor 2 (TIMP2), N-His
Product Overview
BioVenic's Recombinant Canine Metalloproteinase Inhibitor 2 (TIMP2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 14.7 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Canine metalloproteinase inhibitor 2 (TIMP-2) is a protein that regulates the activity of matrix metalloproteinases (MMPs), enzymes that break down components of the extracellular matrix. It plays a significant role in maintaining tissue homeostasis by inhibiting MMPs, thereby preventing excessive degradation of the matrix, which is crucial in processes like tumor invasion and metastasis. TIMP-2 is also involved in the activation of certain MMPs, particularly MMP-2, and is implicated in the progression of canine mammary tumors.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.