This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Canine Platelet-Activating Factor Acetylhydrolase (PLA2G7)
Product Overview
BioVenic's Recombinant Canine Platelet-Activating Factor Acetylhydrolase (PLA2G7) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 50.0 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Platelet-activating factor (PAF) in canines is a potent lipid mediator that plays a significant role in immune response, inflammation, and platelet aggregation. It is involved in the activation of neutrophils, leading to increased calcium concentration and oxygen radical generation, which are crucial for the innate immune response against bacteria and other microorganisms. PAF also mediates the aggregation of platelets, which is an essential aspect of hemostasis and inflammation. Its activation of platelets suggests a close link between hemostasis and neutrophil activation in dogs, providing insight into their response to infection.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.