This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Canine Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2), N-His
Product Overview
BioVenic's Recombinant Canine Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2), N-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 70.4 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine Receptor Tyrosine-Protein Kinase ErbB-2 (ERBB2), also known as HER2, is a key receptor tyrosine kinase involved in cell growth and differentiation. In dogs, ERBB2 is overexpressed in some cancers, such as malignant mammary tumors, and is associated with poor prognosis. It activates downstream signaling pathways like PI3K/AKT and MAPK, promoting cell proliferation and survival. ERBB2 is also implicated in drug resistance mechanisms in cancer treatment. In veterinary medicine, targeting ERBB2 is a potential therapeutic strategy for cancers that overexpress this receptor.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.