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Recombinant Clostridium perfringens Toxin A (tcdA), N-His
Product Overview
BioVenic's Recombinant Clostridium perfringens Toxin A (tcdA), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 66.3 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Clostridium perfringens toxin A, also known as Alpha Toxin (CPA or PLC), is a key virulence factor in veterinary medicine. It is a zinc-dependent phospholipase C that damages cell membranes by degrading phospholipids, leading to hemolysis and tissue necrosis. In animals, CPA causes diseases such as enteritis, enterotoxemia, and gas gangrene, making it a significant threat to livestock health. Understanding and neutralizing CPA is crucial for developing preventive and therapeutic strategies against clostridial diseases in veterinary practice.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.