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Recombinant Feline Caspase-1 (CASP1)
Product Overview
BioVenic's Recombinant Feline Caspase-1 (CASP1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.1 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Feline Caspase-1 (CASP1) is a key cysteine protease involved in inflammation and pyroptosis. It activates inflammasomes to mature and release IL-1β and IL-18, playing a crucial role in immune responses. CASP1 also cleaves gasdermin D (GSDMD) to induce pyroptosis, a pro-inflammatory form of cell death. Abnormal function of Caspase-1 in cats may be associated with various inflammatory diseases, highlighting its importance in regulating immune responses and maintaining tissue homeostasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.