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Recombinant Goat Interleukin Family Protein (IL-10), N-His
Product Overview
BioVenic's Recombinant Goat Interleukin Family Protein (IL-10), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 22.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Goat interleukin family protein IL-10 (IL-10) is a potent anti-inflammatory cytokine that plays a significant role in immune regulation and inflammation control in goats. It is primarily secreted by antigen-presenting cells such as activated T cells, monocytes, B cells, and macrophages. IL-10 downregulates the expression of inflammatory cytokines like TNF-α, IL-6, and IL-1 in macrophages, thereby inhibiting inflammation. This protein also enhances B cell survival, proliferation, and antibody secretion, and it can block NF-κB activity, participating in the JAK-STAT signaling pathway. IL-10 is essential for maintaining immune homeostasis and has potential clinical applications in suppressing rejection after organ transplantation and treating inflammatory diseases.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.