Recombinant Mouse C-C Motif Chemokine 2 (Ccl2), C-His

Mouse C-C Motif Chemokine 2 (Ccl2) is a cytokine that functions as a ligand for C-C chemokine receptor CCR2. It plays a crucial role in immunoregulatory and inflammatory processes by mediating the chemotaxis of monocytes, memory T cells, and dendritic cells to sites of inflammation. In mice, Ccl2 is involved in various physiological and pathological conditions. For example, it has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. Additionally, Ccl2 has been shown to affect metabolic processes and is involved in the regulation of mitochondrial biogenesis and autophagy. Researchers study Ccl2 to understand its role in immune responses, inflammation, and metabolism, which can lead to strategies for managing related diseases and improving overall health in mice.