Recombinant Mouse CD166 Antigen (Alcam), C-Fc

Mouse CD166 Antigen, also known as Alcam, is a cell adhesion molecule expressed in leukocytes and epithelial cells, involved in cell interactions and migration. In mouse models, CD166 is used to study cell adhesion and migration mechanisms in inflammation and tumor metastasis. Research has demonstrated that CD166 plays a crucial role in the homing of lymphocytes to sites of inflammation and in the adhesion of tumor cells to endothelial cells, facilitating metastasis. The molecule is also implicated in the regulation of immune responses, as it can modulate the activation and differentiation of T cells. In the context of cancer, CD166 has been identified as a potential biomarker for various malignancies, and its expression levels correlate with tumor progression and patient prognosis. Targeting CD166 in therapeutic strategies may offer new approaches to inhibit tumor spread and improve clinical outcomes in oncology.