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Recombinant Mouse Inducible T-Cell Costimulator (ICOS), C-His

Cat. No.AP2C823

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Inducible T-Cell Costimulator (ICOS), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 22.7 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 22.7 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Inducible T-Cell Costimulator is a co-stimulatory molecule on T cells involved in T cell activation and function regulation. It enhances T cell activation and proliferation and promotes cytokine production. Studies on ICOS have revealed how co-stimulatory signals fine-tune T cell responses, with implications for developing immune checkpoint inhibitors that can either enhance anti-tumor immunity or suppress pathogenic immune responses in autoimmune conditions.

Protein Mouse Inducible T-Cell Costimulator (ICOS)
Protein Synonym Activation-inducible lymphocyte immunomediatory molecule;
CD28 and CTLA-4-like protein; CCLP; CD28-related protein 1; CRP-1
Gene ID 54167
UniProt ID Q9WVS0

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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