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Recombinant Mouse Interleukin-1 Receptor Type 1 (IL-1RI), C-His
Product Overview
BioVenic's Recombinant Mouse Interleukin-1 Receptor Type 1 (IL-1RI), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 67.0 kDa. The purity is>90%.
Specifications
Target Information
Mouse Interleukin-1 Receptor Type 1 (IL-1RI) is a receptor for interleukin-1 (IL-1), a pro-inflammatory cytokine involved in immune response and inflammation. IL-1RI is expressed on various cell types, including immune cells, and its activation leads to the recruitment of adaptor proteins like MyD88, triggering signaling cascades such as NF-kappa-B and MAPK pathways. These pathways regulate the expression of genes involved in inflammation, immune response, and cell survival. IL-1RI plays a crucial role in mediating the effects of IL-1 on immune and inflammatory responses. It is implicated in various inflammatory diseases, including rheumatoid arthritis and sepsis. Targeting IL-1RI has been explored as a therapeutic strategy for these conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.