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Recombinant Mouse SIGLEC-I (Siglec15), C-His
Product Overview
BioVenic's Recombinant Mouse SIGLEC-I (Siglec15), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 36.9 kDa. The purity is>90%.
Specifications
Target Information
Mouse SIGLEC-I (Siglec15) is a member of the sialic acid-binding immunoglobulin-type lectin (Siglec) family, which are involved in immune regulation. Siglec15 is expressed on immune cells such as macrophages and dendritic cells. It functions as an inhibitory receptor, negatively regulating immune responses by recruiting phosphatases like SHP-1 upon ligand binding. This interaction helps maintain immune homeostasis and prevents excessive inflammation. Siglec15 has been implicated in various immune-related processes, including autoimmune diseases and cancer. Targeting Siglec15 may offer therapeutic potential for modulating immune responses in these conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.