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Recombinant Sheep Metalloproteinase Inhibitor 1 (TIMP1)
Product Overview
BioVenic's Recombinant Sheep Metalloproteinase Inhibitor 1 (TIMP1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.2 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Sheep TIMP1 (Tissue Inhibitor of Metalloproteinases-1) is a protein that plays a multifaceted role in the biology of sheep, particularly in the regulation of the extracellular matrix (ECM) and modulation of various biological processes. It is known to inhibit metalloproteinases (MMPs), which are enzymes responsible for the degradation of ECM components such as collagen and elastin. By binding to MMPs, TIMP1 prevents excessive ECM degradation, thus maintaining tissue structure and stability. Furthermore, TIMP1 has been implicated in cell proliferation, migration, and anti-apoptotic activities, suggesting its involvement in tissue repair and inflammation. In the context of the immune system, TIMP1 may also play a role in immune modulation and inflammation response
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.