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Native Bovine Pituitary Fibroblast Growth Factor (FGF2)

Product Overview

BioVenic's Native Bovine Pituitary Fibroblast Growth Factor (FGF2) is a native protein derived from Bovine Pituitary.

Specifications

Type Native Protein

Species Bovine

Source Pituitary

Predicted Molecular Weight 17 kDa

Physical State Lyophilized

Formulation PBS, 0.1 mg/ml BSA.

Target Information

Fibroblast growth factor 2 acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. It also acts as an integrin ligand which is required for FGF2 signaling. It binds to integrin ITGAV:ITGB3. It plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. It also functions as a potent mitogen in vitro. Previous study has shown that FGF2 seems to play a modulatory role in bovine corpus luteum development or luteolysis, differentially regulating steroidogenesis and angiogenic factors as well as PGF2α actions.

Protein Bovine Fibroblast Growth Factor (FGF2)

Protein Synonym Fibroblast Growth Factor; FGF2; FGF; Fibroblast Growth Factor 2

Gene ID 281161

UniProt ID P03969

Shipping and Storage

Store at -20°C. Avoid freeze and thaw cycles.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Piotrowska-Tomala, K. K. et al. The effect of basic fibroblast growth factor 2 on the bovine corpus luteum depends on the stage of the estrous cycle and modulates prostaglandin F(2α) action. Animal : an international journal of animal bioscience. 2021, 15: 100048.