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Recombinant Swine Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B), N-His

Cat. No.AP9C747

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Swine Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.2 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Swine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 29.2 kDa
Molecular Weight 32.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Swine tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), also known as osteoprotegerin (OPG), is a secreted glycoprotein that modulates bone metabolism by inhibiting bone resorption. It serves as a decoy receptor for RANKL, preventing its interaction with RANK and thus suppressing osteoclast formation and activation. In swine, TNFRSF11B plays a role in immune regulation and bone homeostasis, affecting the balance between bone formation and resorption.

Protein Swine Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B)
Protein Synonym TNFRSF11B; TNFRSF11-B; OCIF; OPG; TR1; Tumor Necrosis Factor Receptor Superfamily Member 11b; Osteoclastogenesis Inhibitory Factor
Gene ID 100049688
UniProt ID A0A8W4FAC7

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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