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Bovine Claudin-2 (CLDN2) ELISA Kit-Sandwich
Product Overview
BioVenic Bovine Claudin-2 (CLDN2) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Claudin-2 (CLDN2) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Claudin-2 is primarily expressed in cation-leaky epithelia, such as the kidney proximal tubule. Overexpression of claudin-2 in cells lacking it leads to increased permeability for small cations. Claudin-2 has also been shown to form paracellular channels for water. Bovine Claudin-2 is encoded by the CLDN2 gene in cattle. Claudin-2 is a tight junction protein that mediates paracellular water transport in intestinal epithelia, making them "leaky".
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zhang, Y.-g. et al. Tight junction CLDN2 gene is a direct target of the vitamin D receptor. Scientific reports. 2015, 5: 10642.