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Rabbit Heparin Cofactor II (HCII) ELISA Kit-Sandwich

Cat. No.EK3F185

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Rabbit Heparin Cofactor II (HCII) ELISA Kit-Sandwich is designed for the quantitative determination of Rabbit HCII in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Rabbit HCII
Target Species Rabbit
Species Reactivity Rabbit
Detection Range 3.13-200 U/L
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Heparin Cofactor II is encoded by the SERPIND1 gene in rabbits. It acts as a thrombin inhibitor and is activated by glycosaminoglycans, such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II becomes the primary thrombin inhibitor, taking the role of antithrombin III (AT). In rabbits, the metabolism and distribution of HCII is characterized by significant features. It has been shown that HCII is cleared more rapidly than antithrombin (AT) in rabbits, and its distribution in the intravascular fraction is proportionally higher.

Target/Biomarker Rabbit HCII
Target Synonym SERPIND1; HC2; HCF2; HC II; HLS2; LS2; Serpin D1; Serpin Peptidase Inhibitor Clade D Member 1; Protease inhibitor leuserpin-2
Gene ID 100009170
UniProt ID P47776

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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