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Bovine Glycogen Phosphorylase, Brain Form (PYGB) ELISA Kit-Sandwich

Name: Bovine Glycogen Phosphorylase, Brain Form (PYGB) ELISA Kit-Sandwich
SKU: EK11F930
Rating: 5 (1 reviews)

Cat. No.EK11F930

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Glycogen Phosphorylase, Brain Form (PYGB) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Glycogen Phosphorylase, Brain Form (PYGB) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine PYGB.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Glycogen Phosphorylase, Brain Form (PYGB) is an enzyme that plays a crucial role in glycogenolysis-the breakdown of glycogen into glucose subunits. It catalyzes the rate-limiting step in glycogenolysis by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. Bovine Glycogen Phosphorylase, Brain Form is encoded by the PYGB gene in cattle. It has been identified as a novel metabolic target with potential applications in the management and/or prevention of metastasis in breast cancer.

Target/Biomarker Bovine PYGB

Target Synonym glycogen phosphorylase B; glycogen phosphorylase, brain form; brain glycogen phosphorylase; phosphorylase, glycogen; brain

Gene ID 505560

UniProt ID Q3B7M9

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Altemus, M. A. et al. Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes. PloS one. 2019, 14: e0220973.