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Feline Beta-2-microglobulin (B2M) ELISA Kit-Sandwich

Cat. No.EK8F254

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Feline Beta-2-microglobulin (B2M) ELISA Kit-Sandwich is designed for the quantitative determination of Feline B2M in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Feline B2M.
Target Species Feline
Species Reactivity Feline
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Beta-2-microglobulin is encoded by the B2M gene in cats. It is a component of the class I major histocompatibility complex (MHC). It is involved in the presentation of peptide antigens to the immune system. Glomerular-filtered Beta-2-microglobulin is reabsorbed and broken down in the proximal convoluted tubules. Dysfunction in this process can indicate kidney disease, as evidenced by the presence of Beta-2-microglobulin in urinary protein due to the absence of endocytosis mediated by the megalin-cubilin complex.

Target/Biomarker Feline B2M
Target Synonym beta-2-microglobulin; B2M; β2-MG; β2-microglobulin
Gene ID 494145
UniProt ID Q5MGS7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Katagi, Michio, et al. "Comparisons of β2-microglobulin, apolipoprotein A1, and immunoglobulins (IgG and IgM) detected in the serum and urine from individual cats." Austral journal of veterinary sciences 55.3 (2023): 197-202.
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