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Guinea Pig Nuclear factor NF-kappa-B p105 subunit (NF-κBp105) ELISA Kit-Sandwich

Cat. No.EK3F87

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Guinea Pig Nuclear factor NF-kappa-B p105 subunit (NF-κBp105) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig NF-κBp105 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Guinea Pig NF-κBp105.
Target Species Guinea Pig
Species Reactivity Guinea Pig
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that regulate DNA transcription, cytokine production, and cell survival. NFKB1 encodes the p105 subunit of NF-κB, which undergoes processing to produce the NF-κB p50 subunit. Among transcription factors, NFKB1 is the most abund antly expressed in macrophages, which are crucial cellular drivers of inflammation and immunity. Guinea pigs are extensively used as models for respiratory diseases, particularly asthma and airway inflammation. The NF-κB pathway is very important in the studies of airway hyperresponsiveness.

Target/Biomarker Guinea Pig NF-κBp105
Target Synonym NF-KB1; EBP-1; KBF1; NF-Kappa-B; NFKB-P105; NFKB-P50; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1; Nuclear factor NF-kappa-B p105 subunit; NFkB; Nuclear Factor Kappa B

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Somma, Domenico et al. "Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells." Frontiers in immunology vol. 12 669906. 13 Oct. 2021.
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