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Hamster Leptin (LEP) ELISA Kit-Sandwich
Product Overview
BioVenic Hamster Leptin (LEP) ELISA Kit-Sandwich is designed for the quantitative determination of Hamster LEP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Leptin, also referred to as the obesity protein, is a hormone primarily produced by adipocytes, the cells in adipose tissue. It functions by binding to and activating the long form of leptin receptors (LEPRb), which are extensively expressed in various brain regions, particularly the hypothalamus. Research indicates that effective leptin signaling to the brain is involved in reducing hyperphagia in hamsters that have been refed with a low-fat (LF) diet. Leptin also influences immune function and bone growth, with low leptin levels associated with increased bone mineral apposition rate in Siberian hamsters.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zhao, Ying et al. "Leptin resistance was involved in susceptibility to overweight in the striped hamster re-fed with high fat diet." Scientific reports vol. 8,1 920. 17 Jan. 2018.; Kokolski, Marie et al. "Photoperiod-Induced Increases in Bone Mineral Apposition Rate in Siberian Hamsters and the Involvement of Seasonal Leptin Changes." Frontiers in endocrinology vol. 8 357. 19 Dec. 2017