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Mouse Anti-Bovine CD80 Monoclonal Antibody-[PE]
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine CD80. It can be applied to FCM assay of bovine CD80.
Specifications
Target Information
Bovine CD80, also known as B7-1, is a co-stimulatory molecule expressed on the surface of antigen-presenting cells such as dendritic cells, activated macrophages, and activated B cells. It plays a crucial role in T cell activation by interacting with the T cell receptor CD28 and the inhibitory receptor CTLA-4 (CD152) on T cells. This interaction provides the necessary co-stimulatory signals for T cell proliferation and differentiation, enhancing the immune response.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Suvas, Susmit, et al. "Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma." Journal of Biological Chemistry 277.10 (2002): 7766-7775.