Mouse Anti-Canine Adenylate Kinase 3 (AK3) Monoclonal Antibody

Canine adenylate kinase 3 (AK3) is a crucial enzyme involved in the regulation of adenine nucleotide metabolism, catalyzing the reversible reaction of ATP and AMP to produce two ADP molecules. This enzyme is primarily localized in the mitochondrial matrix, where it plays a significant role in maintaining cellular energy homeostasis and regulating mitochondrial energy metabolism. AK3 is essential for normal cellular functions, including growth, differentiation, and motility. Its activity is particularly important in high-energy-demand tissues, such as muscle and brain. Dysregulation of AK3 has been linked to various metabolic disorders and may influence cancer cell metabolism, highlighting its potential as a therapeutic target in canine health and disease management.