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Rabbit Anti-Bovine Transthyretin (TTR) Polyclonal Antibody-[FITC]

Cat. No.VD11N895

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine transthyretin. It is antigen affinity purified. It can be applied to WB, IHC and IF/ICC assays of bovine transthyretin.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone J17N22
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Transthyretin
Isotype IgG
Immunogen Recombinant protein of transthyretin
Purification Antigen Affinity Purified
Conjugation FITC
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine transthyretin (TTR) is a protein primarily synthesized by the liver and the choroid plexus in the brain. It plays a critical role in the transport of thyroid hormones, particularly thyroxine (T4), from the bloodstream to target tissues. Additionally, TTR is involved in the transport of retinol (vitamin A) by binding to retinol-binding protein (RBP), ensuring its delivery from the liver to various cells. This protein also acts as a negative acute phase reactant, with its serum concentration decreasing in response to inflammation, trauma, or stress. In cattle, TTR is implicated in adipogenesis, potentially influencing the differentiation of adipocytes and the expression of key adipogenic markers such as PPARγ and FABP4.

Target Bovine Transthyretin
Target Synonym TTR
Gene ID 280948
UniProt ID O46375

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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