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Mouse Anti-Bovine Lysine Specific Histone Demethylase 1A (LSD1) Monoclonal Antibody

Cat. No.VD12N409

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine lysine specific histone demethylase 1A. It is purified by affinity chromatography. It can be applied to WB, IHC and IF assays of bovine lysine specific histone demethylase 1A.

Specifications

Application WB; IHC; IF
Clonality Monoclonal
Classification Primary Antibody
Clone M5N23
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Lysine Specific Histone Demethylase 1A
Immunogen Recombinant protein of lysine specific histone demethylase 1A
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Bovine Lysine Specific Histone Demethylase 1A (LSD1/KDM1A) is a FAD-dependent enzyme that catalyzes the oxidative demethylation of histone H3K4me1/2 and H3K9me1/2, playing a crucial role in epigenetic regulation of gene expression. It acts as a transcriptional repressor by removing methyl groups from histones, thereby influencing chromatin structure and gene silencing. LSD1 also interacts with nuclear receptors to activate gene expression in certain contexts, such as androgen-dependent transcription. This enzyme is involved in various cellular processes, including hematopoiesis, embryonic development, and cancer progression.

Target Bovine Lysine Specific Histone Demethylase 1A
Target Synonym LSD1
Gene ID 532997
UniProt ID F1MBS5

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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