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Mouse Anti-Canine Importin Beta 1 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine importin beta 1. It can be applied to WB, ICC/IF, FACS, IP, ChIP and IHC assays of canine importin beta 1.
Specifications
Target Information
Canine importin beta 1 (KPNB1) is a conserved nuclear transport receptor that plays a pivotal role in the nuclear import of proteins containing nuclear localization signals (NLS) in eukaryotic cells, including dogs. It is crucial for various cellular processes such as DNA replication, DNA repair, transcriptional control, and epigenetic regulation of gene expression. In addition to its role in interphase nuclei, Importin Beta 1 is also a global regulator of mitosis, influencing mitotic spindle organization, and function. Overexpression of Importin Beta 1 is observed in many cancer types, suggesting its potential as a therapeutic target in oncology. In dogs, understanding the function of Importin Beta 1 is essential for insights into nuclear transport mechanisms and its implications in health and disease, particularly in cancer biology.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.