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Mouse Anti-Porcine Cell Division Cycle 73 (CDC73) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for cell division cycle 73. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of cell division cycle 73.
Specifications
Target Information
Porcine cell division cycle 73 (CDC73), also known as the parafibromin, is a protein that plays a critical role in the regulation of cell division in pigs. CDC73 is primarily involved in the control of the G1 to S phase transition, a key checkpoint in the cell cycle that ensures proper cell growth and preparation for DNA replication. This protein functions as a component of the CDK8/cyclin C complex, which acts as a kinase and regulates various transcription factors, thereby influencing gene expression patterns that are essential for cell cycle progression. CDC73 is also implicated in the regulation of DNA replication and the maintenance of genomic stability.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Walls, Gerard V., et al. "Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome." Oncogene 36.28 (2017): 4025-4036.