Mouse Anti-Porcine Fat Mass and Obesity Associated (FTO) Monoclonal Antibody

Porcine fat mass and obesity associated (FTO) is a gene that has garnered significant attention in the field of obesity research, including in pigs. The FTO gene is involved in the regulation of energy metabolism and appetite, and it has been associated with fat mass development and obesity in humans. In pigs, which are often used as models for human metabolic studies due to their physiological similarities, the FTO gene is a target of interest for understanding the genetic basis of body fat distribution and obesity. This gene is expressed in various tissues, including the hypothalamus, which is a key region in the brain responsible for appetite control and energy homeostasis. The protein encoded by FTO is involved in epigenetic regulation, particularly in the demethylation of DNA and histones, which can influence gene expression patterns related to energy balance.