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Mouse Anti-Bovine Heat Shock Protein A5 (HSP A5) Monoclonal Antibody

Cat. No.VD8N86

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine heat shock protein A5. It can be applied to WB, IF and ICC assays of bovine heat shock protein A5.

Specifications

Application WB; IF; ICC
Clonality Monoclonal
Classification Primary Antibody
Clone G3N50
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Heat Shock Protein A5
Isotype IgG
Immunogen Purified recombinant bovine heat shock protein A5 (C-terminus) protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Heat shock protein A5, also known as HSP60 or HSPD1, is a molecular chaperone belonging to the HSP60 family of proteins. It plays a crucial role in cellular homeostasis by assisting in the folding, assembly, and stabilization of other proteins, particularly those associated with the mitochondrial matrix. HSP A5 is highly conserved across various species, reflecting its essential function in maintaining protein integrity and preventing the aggregation of misfolded proteins. It is particularly active under stress conditions, such as heat shock, oxidative stress, and other cellular injuries, where it helps to protect cells by refolding denatured proteins and preventing protein aggregation.

Target Bovine Heat Shock Protein A5
Target Synonym HSPA5; GRP78
Gene ID 415113
UniProt ID Q0VCX2

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Elfiky, Abdo A. "SARS-CoV-2 spike-heat shock protein A5 (GRP78) recognition may be related to the immersed human coronaviruses." Frontiers in pharmacology 11 (2020): 577467.
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