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Mouse Anti-Porcine Guanidinoacetate N-Methyltransferase (GAMT) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for guanidinoacetate N-methyltransferase. It is affinity purified by protein A. It can be applied to WB and ELISA assays of guanidinoacetate N-methyltransferase.
Specifications
Target Information
Porcine guanidinoacetate N-methyltransferase (GAMT) is an enzyme that plays a critical role in the creatine biosynthesis pathway in pigs. GAMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to guanidinoacetate, converting it into creatine, which is essential for cellular energy production and muscle function. This enzyme is particularly important in the brain and skeletal muscle, where creatine is used to replenish ATP through the creatine kinase system. GAMT's activity ensures the adequate supply of creatine for maintaining energy homeostasis, especially during periods of high energy demand.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Aksentijević, Dunja, et al. "Age-dependent decline in cardiac function in guanidinoacetate-N-methyltransferase knockout mice." Frontiers in physiology 10 (2020): 1535.