Mouse Anti-Porcine UDP-Glucose Dehydrogenase (UGDH) Monoclonal Antibody

Porcine UDP-glucose dehydrogenase (pUGDH) is an enzyme that catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, a critical step in the biosynthesis of glucuronate, a major component of glucuronic acid conjugates. pUGDH plays a vital role in the UDP-glucose pathway, which is essential for the production of glycosaminoglycans, proteoglycans, and other glycoconjugates that are crucial for various cellular functions, including cell signaling, cell adhesion, and the maintenance of the extracellular matrix. This enzyme is highly expressed in the liver, where it contributes to the detoxification process by facilitating the glucuronidation of harmful substances, such as drugs and toxins, for their subsequent excretion. In pigs, pUGDH may be particularly important for maintaining liver health and supporting the animal's ability to detoxify.