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Recombinant Borreliella burgdorferi Outer Surface Protein C (ospC)

Cat. No.VG9C403

Product TypeVeterinary Antigens

Size 1 mg

Product Overview

BioVenic's Recombinant Borreliella burgdorferi Outer Surface Protein C (ospC) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.9 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacterium
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 27.9 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is 0mM Tris, 500mM Nacl, 2M Urea, 10%glycerol, pH 7.4.

Target Information

Borreliella burgdorferi outer surface protein C (ospC) is a critical lipoprotein involved in the early stages of infection. It plays a significant role in the transmission of the bacterium from ticks to hosts and helps the bacterium evade the host's immune system by inhibiting phagocytosis by macrophages. In veterinary medicine, OspC is used as a target for developing vaccines that can prevent the establishment of infection in animals. These vaccines induce antibodies that bind to OspC, blocking its function and thus preventing the bacterium from successfully infecting the host. Additionally, OspC is used in diagnostic tests to detect antibodies in animals that have been exposed to the bacterium, aiding in the early detection and management of Lyme disease.

Protein Borreliella burgdorferi Outer Surface Protein C (ospC)
UniProt ID Q07337

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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