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Recombinant Bovine Beta-Defensin 1 (DEFB1), N-His-SUMO

Cat. No.AP9C417

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Beta-Defensin 1 (DEFB1), N-His-SUMO is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.0 kDa. The purity is>80% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >80% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 18.0 kDa
Molecular Weight 22 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Bovine beta-defensin 1 is an antimicrobial peptide that is a crucial component of the innate immune system in cattle. It is involved in the body's first line of defense against a range of pathogens, including bacteria responsible for mastitis such as Escherichia coli and Staphylococcus aureus. This protein plays a vital role in immune defense by disrupting the membranes of target microbes, leading to their destruction. It also exhibits immunomodulatory properties, influencing the chemotaxis of dendritic cells and the secretion of cytokines.

Protein Bovine Beta-Defensin 1 (DEFB1)
Protein Synonym B-DF1; DEFB1; BD1; DEF-B1; DEFB101; HBD1
Gene ID 768318
UniProt ID P46159

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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