Recombinant Bovine Fibroblast Growth Factor 4 (FGF4), N-His

Bovine fibroblast growth factor 4 (FGF4) is a crucial protein involved in the developmental processes of cattle, particularly playing a significant role in embryonic development and cell proliferation. As a member of the fibroblast growth factor family, FGF4 is known to stimulate the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origins. It is expressed in various tissues, including the brain, retina, bone matrix, and osteosarcomas, and is involved in tissue maintenance, wound repair, and angiogenesis. FGF4's expression has been identified in the Bovine placenta during early pregnancy, where it is involved in the development and maintenance of the vascular system, especially in endocrine glands. It is also associated with the promotion of proliferation, migration, and survival of responsive cells, highlighting its importance in both physiological and pathological angiogenesis in cattle.