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Recombinant Bovine Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A (FCGR3A), C-His

Cat. No.AP2C258

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A (FCGR3A), C-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 22.4 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System HEK293 Cell
Purity >85% (SDS-PAGE)
Endotoxin < 1.0 EU/mg
Predicted Molecular Weight 22.4 kDa
Physical State Lyophilized
Formulation PBS with 5% Trehalose and 5% Mannitol.

Target Information

In bovines, low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A) is an important immune molecule expressed on monocytes, macrophages, and natural killer (NK) cells. FCGR3A is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), where it recognizes and binds the Fc segment of IgG antibodies to activate NK cells for the elimination of pathogens or tumor cells. Additionally, FCGR3A may also regulate inflammatory responses and immune cell activation in the bovine immune system.

Protein Bovine Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A (FCGR3A)
Protein Synonym IgG Fc receptor III-A; Fc-gamma RIII-alpha; FcgammaRIIIA; CD16a; CD16
Gene ID 281766
UniProt ID P79107

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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