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Recombinant Bovine Major Histocompatibility Complex, Class II, DO Alpha (HLA-DOA), N-His
Product Overview
BioVenic's Recombinant Bovine Major Histocompatibility Complex, Class II, DO Alpha (HLA-DOA), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.4 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) is a key component of the major histocompatibility complex (MHC) in cattle, which plays a central role in the immune response by presenting antigens to T cells. This protein is essential for initiating and regulating immune reactions, particularly for the activation of CD4+ T cells. As part of the MHC class II molecules, HLA-DRA associates with the DR beta chain to form a heterodimer that binds and presents peptides derived from extracellular proteins. This presentation is crucial for T cell recognition and subsequent immune activation, making HLA-DRA a critical factor in immune surveillance and defense against pathogens.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.