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Recombinant Mouse ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2 (BST1), C-His

Cat. No.AP2C768

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2 (BST1), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 34.6 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 34.6 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2, also known as BST1, is an enzyme involved in cell signaling. It regulates intracellular calcium ion concentration, affecting various physiological functions. In research, BST1 is used to explore its potential roles in immune responses and neurological diseases. Studies have shown that BST1 may be involved in the pathogenesis of multiple sclerosis and other neuroinflammatory conditions. By modulating calcium signaling, BST1 can influence the activation and function of immune cells such as T lymphocytes and microglia. Additionally, BST1 has been implicated in the regulation of insulin secretion in pancreatic beta cells, suggesting its potential relevance to diabetes research. The enzyme's activity can be modulated by various factors, including cellular stress and inflammatory cytokines, making it a potential target for therapeutic interventions in several disease contexts.

Protein Mouse ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2 (BST1)
Protein Synonym ADP-ribosyl cyclase 2; Antigen BP3;
BP-3 alloantigen; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPR hydrolase 2; Leukocyte antigen 65 (Ly-65)
Gene ID 12182
UniProt ID Q64277

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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