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Recombinant Canine Leukemia Inhibitory Factor (LIF)

Cat. No.AP1C35

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Leukemia Inhibitory Factor (LIF) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.8 kDa. The purity is>95% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 23.8 kDa
Molecular Weight 22.6 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Canine leukemia inhibitory factor (LIF) is a pleiotropic cytokine that belongs to the interleukin-6 family. It plays a significant role in various biological processes, including immune responses, inflammation, and the regulation of cell growth and differentiation. LIF is involved in the development of several malignancies, where its high expression can enhance tumor cell invasion and migration, and reduce the sensitivity to chemotherapy and radiotherapy, leading to poor prognosis in patients. It is also considered a potential target for cancer therapy.

Protein Canine Leukemia Inhibitory Factor (LIF)
Protein Synonym CDF; D-FACTOR; HILDA; MLPLI; Cholinergic Differentiation Factor; Differentiation-Stimulating Factor; Melanoma-Derived LPL Inhibitor; Emfilermin
Gene ID 403449
UniProt ID A0A8I3Q5S6

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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