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Recombinant Canine Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA), N-His and C-Myc

Cat. No.AP9C578

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA), N-His and C-Myc is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.3 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 42.3 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Target Information

Canine serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) (X155S,X158S) is a pivotal regulatory enzyme in dogs that plays a role in a wide array of cellular processes. This protein is involved in the control of protein phosphorylation, which is crucial for regulating cell signaling, metabolism, and the cell cycle. The PP1-alpha catalytic subunit, particularly with the X155S and X158S variations, may have altered activity or substrate specificity, potentially affecting cellular functions and responses to various stimuli. In veterinary medicine, understanding the function of PPP1CA and its mutants is vital for studying diseases associated with aberrant protein phosphorylation and for developing therapeutic strategies targeting this enzyme.

Protein Canine Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA)
UniProt ID Q8WMS6

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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