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Recombinant Canine Trefoil Factor 3 (TFF3), N-His
Product Overview
BioVenic's Recombinant Canine Trefoil Factor 3 (TFF3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 7.7 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Canine trefoil factor 3 (TFF3) is a protein that plays a significant role in mucosal protection and repair, particularly in the gastrointestinal tract. It is involved in promoting the expression and distribution of tight junction proteins, which are crucial for maintaining the integrity of the intestinal epithelial barrier. TFF3 also has pro-angiogenic properties, contributing to the healing of the mucosal layer through increased blood supply. Additionally, it interacts with mucins to form a protective gel layer that isolates microbes from the epithelial cells, reducing direct stimulation and inflammation. TFF3 is also known to inhibit inflammatory responses and modulate the expression of inflammatory mediators, making it an important factor in the regulation of the immune system and inflammation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.