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Recombinant Canine Tyrosine-Protein Kinase Receptor (NTRK2), C-His
Product Overview
BioVenic's Recombinant Canine Tyrosine-Protein Kinase Receptor (NTRK2), C-His is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 45.6 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine Tyrosine-Protein Kinase Receptor (NTRK2), also known as TrkB, is a receptor tyrosine kinase involved in the development and maturation of the central and peripheral nervous systems. It regulates neuron survival, proliferation, and differentiation by binding to neurotrophins such as brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3). In dogs, NTRK2 plays a crucial role in maintaining neural circuits and synaptic plasticity. It also activates downstream signaling pathways like MAPK and PI3K/AKT, which promote nerve growth and cell survival. Dysregulation of NTRK2 has been implicated in neurodegenerative disorders and cancer.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.