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Recombinant Feline Beta-Hexosaminidase Subunit Beta (HEXB)

Cat. No.AP2C110

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Recombinant Feline Beta-Hexosaminidase Subunit Beta (HEXB) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 60.4 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 60.4 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

Feline Beta-Hexosaminidase Subunit Beta (HEXB) is a key component of lysosomal beta-hexosaminidase, which degrades GM2 ganglioside in conjunction with GM2 activator protein. Mutations in the HEXB gene lead to GM2 accumulation in neurons, causing severe neurodegenerative diseases like Sandhoff disease. This mutation has been identified in feline models for Sandhoff disease.

Protein Feline Beta-Hexosaminidase Subunit Beta (HEXB)
Protein Synonym HEXB; Beta-hexosaminidase subunit beta
Gene ID 493928
UniProt ID P49614

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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