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Recombinant Feline Brevican Core Protein (BCAN)
Product Overview
BioVenic's Recombinant Feline Brevican Core Protein (BCAN) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 45.0 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
In felines, Brevican Core Protein (BCAN) is a proteoglycan highly expressed in the central nervous system, involved in forming the brain extracellular matrix and regulating synaptic plasticity. BCAN plays a role in neuronal development, particularly in differentiation and maturation. It stabilizes molecular networks on neuronal surfaces by binding to hyaluronan (HA) and is involved in synaptic plasticity, post-injury repair, and neurodegenerative diseases like Alzheimer's. Additionally, BCAN is highly expressed in gliomas, where it may promote tumor cell adhesion and migration.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.