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Recombinant Feline Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R), N-His-SUMO
Product Overview
BioVenic's Recombinant Feline Serum Amyloid A Protein (SAA1), N-His-B2M is a recombinant protein expressed from E.coli. Its predicted molecular weight is 24.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Feline macrophage colony-stimulating factor 1 receptor (CSF1R) is a type I transmembrane receptor that is crucial for the development, function, and survival of macrophages and their precursors in cats. This receptor is activated by binding to its ligands, CSF-1 and IL-34, which triggers intracellular signaling pathways that regulate cellular proliferation, differentiation, and activation. CSF1R plays a vital role in the immune response, particularly in the innate immune system, by controlling the number and activity of macrophages. It is also implicated in the pathogenesis of various diseases, including certain types of cancer and inflammatory conditions. In veterinary medicine, understanding CSF1R's function is key to developing targeted therapies for feline diseases involving macrophage dysregulation.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.