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Recombinant Influenza A H3N2 Neuraminidase (NA), C-His
Product Overview
BioVenic's Recombinant Influenza A H3N2 Neuraminidase (NA), C-His is a recombinant protein expressed from Baculovirus-insect cell. Its predicted molecular weight is 53.9 kDa. The purity is>90% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL).
Specifications
Target Information
Influenza A virus subtype H3N2 (A/H3N2) is a strain that causes the flu and can infect both birds and mammals. Neuraminidase (NA) facilitates the removal of terminal sialic acid residues from viral and cellular glycoconjugates. In addition to its usual enzymatic function, NA in influenza viruses can also serve as a receptor-binding protein-a role typically associated with hemagglutinin (HA). In the case of Influenza A(H3N2) viruses, three specific NA amino acid residues-T148, D151, and the recently identified H150-have been linked to NA-mediated hemagglutination.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Gao, Rongyuan et al. "New insights into the neuraminidase-mediated hemagglutination activity of influenza A(H3N2) viruses." Antiviral research vol. 218 (2023): 105719.